Roaccutane 20 mg Isotretinoin
245.70$ – 702.00$
Roaccutane 20mg (Isotretinoin) should only be prescribed by or under the supervision of physicians experienced in the use of systemic retinoids in the treatment of severe acne and a thorough knowledge of the risks of isotretinoin and monitoring it imposes.
Dosage Roaccutane 20 mg Isotretinoin Soft Capsule Box of 30
– Roaccutane 20 mg Isotretinoin should only be prescribed by or under the supervision of physicians experienced in the use of systemic retinoids in the treatment of severe acne and a thorough knowledge of the risks of isotretinoin and monitoring it imposes.
– The capsules should be swallowed during meals, once or twice a day.
– Adolescents, adults and seniors:
. Treatment with Roaccutane 20mg (Isotretinoin) should be initiated at 0.5 mg / kg / day.
The therapeutic response to isotretinoin and some of the side effects are dose-dependent and vary from patient to patient. This requires an individual adjustment of the dose during treatment. For most patients, the dose is between 0.5 and 1 mg / kg / day.
. The rates of prolonged remission and relapse after isotretinoin therapy depend more on the total cumulative dose than on the duration of treatment or daily dosage. Continued treatment beyond a cumulative dose in the range of 120 to 150 mg / kg has been shown to produce no significant additional benefit. The duration of treatment depends on the individual daily dose. A course of treatment lasting 16 to 24 weeks is usually sufficient to achieve remission.
. In the majority of patients, a complete cure of acne is obtained after a single cure. In case of confirmed relapse, a new course of isotretinoin may be considered with the same daily dosage and the same cumulative therapeutic dose. As the improvement of acne can continue until 8 weeks after stopping treatment, a new cure before the end of this period should not be considered.
– Patients with severe renal insufficiency:
In patients with severe renal impairment, treatment should be initiated at a lower dose (eg 10 mg / day). The dosage will then be gradually increased up to 1 mg / kg / day or up to the maximum tolerated dose by the patient (see Warnings and Precautions section).
Roaccutane 20 mg Isotretinoin is not indicated for the treatment of prepubertal acne and is not recommended for children under 12 years of age.
– intolerant patients:
In patients with severe intolerance at the recommended dose, treatment may be continued at a lower dose, thus exposing the patient to a longer duration of treatment and an increased risk of relapse. In order to ensure the best possible efficacy in these patients, treatment should normally be continued at the maximum tolerated dose.
– Roaccutane 20 mg Isotretinoin is contraindicated in pregnant or breastfeeding women:
. pregnancy: pregnancy is an absolute contraindication to treatment with isotretinoin. The occurrence, despite contraceptive measures, of pregnancy during treatment with isotretinoin or within one month after discontinuation, carries a very high risk of major malformations in the fetus. Fetal malformations associated with isotretinoin treatment include central nervous system abnormalities (hydrocephalus, malformations or cerebellar abnormalities, microcephaly), facial dysmorphism, cleft palate, abnormalities of the outer ear (absence of external ear, auditory canal external small or absent), ocular abnormalities (microphthalmia), cardiovascular (conotruncal anomalies such as tetralogy of Fallot, transposition of large vessels, interventricular communication), abnormalities of the thymus and parathyroid glands. There is also an increased risk of spontaneous abortion. If pregnancy occurs in a woman treated with isotretinoin, treatment should be discontinued and the patient should be referred to a specialist or teratology specialist for evaluation and counseling.
NOT RECOMMENDED :
– Children: Roaccutane 20mg (Isotretinoin) is not indicated for the treatment of prepubertal acne and is not recommended for children under 12 years of age.
– Concomitant administration of isotretinoin and vitamin A should be avoided due to the risk of hypervitaminosis A.
Side effects Roaccutane 20mg
The most common side effects observed during treatment with isotretinoin are dryness of the mucous membranes, especially the labial (cheilitis), nasal (epistaxis) and ocular (conjunctivitis); and a dry skin. These side effects, as well as some others, are dose-dependent. In general, most adverse effects are reversible after decreasing the dose or discontinuing treatment; some, however, persist after stopping treatment.
Very rare (<= 1/10000): Bacterial (cutaneo-mucous) infection with Gram-positive germs.
– Circulatory and lymphatic disorders: