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Norditropin Nordiflex 5mg 15IU

210.60$2,340.00$

Norditropin Nordiflex 5mg 15IU is used to treat the following:

children with growth failure caused by very low or no production of growth hormone
short stature in children with Noonan syndrome
short stature in children with Turner syndrome

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Norditropin Nordiflex 5mg 15IU (somatropin)

Norditropin Nordiflex5 mg/1.5 mL (Human Growth Hormone)

Please read these instructions carefully before using this pen

Norditropin Nordiflex 5mg 15IU is used to treat the following:

children with growth failure caused by very low or no production of growth hormone
short stature in children with Noonan syndrome
short stature in children with Turner syndrome
children with short stature born small for gestational age (SGA) with no catch-up growth by age 2-4 years
adults who do not make sufficient growth hormone
Norditropin is injected using Norditropin Nordilet 5mg 15IU, a multi-dose disposable 1.5 mL prefilled pen. Norditropin NordiFlex contains several doses of growth hormone solution. A dose is injected under the skin in the evening 6-7 times a week. 

Norditropin Nordiflex 5mg 15IU is available in three strengths: 5 mg/1.5 mL, 10 mg/1.5 mL and 15 mg/1.5 mL (i.e. with a concentration of 3.3 mg/mL, 6.7 mg/mL and 10.0 mg/mL respectively).

Throw away Norditropin Nordilet 5mg 15IU when the cartridge is empty.

Medicines are sometimes prescribed for purposes other than those listed in a patient guide. You should ask your doctor about any concerns and refer to the professional labeling for additional information.

What does Norditropin Nordiflex 5mg 15IU contain?

The cartridge in Norditropin NordiFlex contains human growth hormone called somatropin (so-ma-tro-pin) made through biotechnology. It is identical to the growth hormone produced in the human body.

The cartridge contains other ingredients: Histidine, Poloxamer 188, Phenol, Mannitol and Water for Injection.

Who should not use Norditropin Nordilet 5mg 15IU?

Do not use Norditropin Nordiflex 5mg 15IU if you have any of the following conditions:

child with closed epiphyses (closed bone growth plates)
child with Prader-Willi syndrome who is also severely obese or has significant respiratory impairment
allergic to phenol or any other ingredients in the medicine
had a kidney transplant
pregnant
breast-feeding
active cancer or other forms of tumor
acute critical illness due to certain types of heart or abdomen surgery, trauma or acute respiratory failure
What should you consider if you are pregnant or breast-feeding?

If you become pregnant while you are using Norditropin Nordilet 5mg 15IU, you are recommended to stop the treatment and discuss this with your doctor.

You are recommended not to use Norditropin Nordilet 5mg 15IU while you are breast-feeding because growth hormone might pass into your milk.

Be sure to tell your doctor if you:

have diabetes mellitus
had cancer or other forms of tumor
are pregnant, planning to be pregnant or breastfeeding
had a kidney transplant
If any of the above applies to you, Norditropin Nordiflex 5mg 15IU may not be suitable. Your doctor will give you advice.

How should I use Norditropin Nordilet 5mg 15IU?

Carefully follow the “Instructions for Use” on the other side of this patient guide.

You should inject Norditropin Nordiflex 5mg 15IU under the skin in the evening just before bedtime. You should change the injection area so you do not harm your skin.
1 Preparing Norditropin NordiFlex 5 mg/1.5 mL for injection

A. Pull off the pen cap and check if the growth hormone solution is clear and colorless by turning Norditropin Nordilet 5mg 15IU upside down once or twice and view the solution through the residual scale window. DO NOT use Norditropin Nordilet 5mg 15IU if the growth hormone solution is cloudy or contains particles. Use it only if it is clear and colorless.

Wash hands well and dry completely.

Wipe the front rubber stopper on the threaded plastic cap with an alcohol swab.

B. Place a new NovoFine disposable needle onto Norditropin Nordilet 5mg 15IU immediately before use. Remove the protective tab from the disposable needle and screw the needle tightly onto Norditropin NordiFlex. Pull off the outer and inner needle caps. Never place a disposable needle on your Norditropin NordiFlex until you are ready to give an injection. Remove the needle immediately after use. If the needle is not removed, some growth hormone may be expelled from Norditropin Nordilet 5mg 15IU.

2 Performing an air shot

Do an air shot before starting a new Norditropin Nordilet 5mg 15IU as follows:

Small amounts of air may collect in the needle and cartridge. To avoid injecting air and ensure proper dosing, set the dosage selector to 0.025 mg. Each line between labeled dosages is 0.025 mg.

C. Dial 0.025 mg

D. Hold Norditropin Nordilet 5mg 15IU with the needle pointing up, tap the cartridge gently with your finger a few times to raise any air bubbles to the top of the cartridge.

E. Still holding Norditropin Nordilet 5mg 15IU with the needle up, press the push button all the way in. A drop of growth hormone should appear at the needle tip. If not, repeat the procedure, no more than 4 times.

If a drop of growth hormone still does not appear, call 1-888-NOVO-444 for help.

3 Setting the dose

F. Check that the dose selector is set at 0.0. Dial the number of mg (milligram) that you need to inject. The dose can be changed up or down by turning the dose selector in either direction. When dialing back, be careful not to press the push button as growth hormone liquid will come out.

DO NOT use the clicking sound as a guide for selecting dose.

The numbers on the residual scale can be used to estimate the mg left in the cartridge. DO NOT use these numbers to measure the growth hormone dose.

You cannot set a dose higher than the number of mg left in the cartridge. Use a new Norditropin Nordilet 5mg 15IU pen to inject the remaining amount of your dose. Be sure to remember the dose already received with the first dose. For example, if your dose is 0.6 mg and you can only set the dose selector to 0.4 mg, you will need to inject an additional 0.2 mg with a new Norditropin Nordilet 5mg 15IU.

4 Giving the injection

Use the injection procedure recommended by your doctor or healthcare professional.

G. This product is for subcutaneous use only. Insert the needle under the skin and deliver the dose by pressing the push button all the way in. Press the push button only when injecting.

After the injection, the needle should remain under the skin for at least 6 seconds. Keep the push button fully depressed until the needle is removed from the skin. This will ensure that the full dose has been delivered. Vary the injection site using the injection procedure recommended by your doctor.

After the injection, check the dosage indicator window to make sure it shows zero (0.0). If zero does not appear, you did not receive the full dose

Before use MUST keep refrigerated. (2ºC-8ºC/36ºF-46ºF). Do not store with needles. After initial injection, EITHER keep refrigerated for 4 weeks OR store not above 25ºC (77ºF) for 3 weeks. Do not freeze. Discard unused portion. Avoid direct light. Keep out of the reach and sight of children. For subcutaneous administration only. Please read the enclosed leaflet before use.

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